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Updated: Sep 17, 2025

Assays for Validating Histone Acetyltransferase Inhibitors
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新型二胺酸衍生物对希斯脱乙酶的抑制作用 1 1

Jhawn G Saul1,2, Andrew E Huckleby1,2, Maia C Gugello2

  • 1Department of Biochemistry and Microbiology at Oklahoma State University-Center for Health Sciences, College of Osteopathic Medicine, Tulsa, OK 74464, USA.

Frontiers in bioscience (Scholar edition)
|July 4, 2025
PubMed
概括

化合物4表现出比化合物6更强烈的结合和抑制作用对基因素脱乙酶1 (HDAC1) 的作用. 这种选择性HDAC1抑制为开发新的癌症疗法提供了一个有希望的策略.

关键词:
酶抑制剂是一种酶抑制剂.基因组脱乙酶1 基因组脱乙酶1素酸的含量是多少?分子动力学模拟模拟

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