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在初级T细胞中删除Cdc42后的转录适应

Adam M Rochussen1, Claire Y Ma1, Gillian M Griffiths1

  • 1University of Cambridge, Cambridge Institute for Medical Research, Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

Journal of cell science
|July 4, 2025
PubMed
概括

细胞毒性T淋巴细胞 (CTLs) 惊人地恢复并增强分泌和细胞毒性,即使Cdc42基因被删除. 这突显了T细胞适应失去重要基因的能力.

关键词:
美国疾病预防控制中心42 CDC42这就是CRISPR/Cas9的作用.在Rho GTPase中.一个T细胞细胞.转录性适应 转录性适应

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