互惠多网络噪音标签学习 (MMNNLL) 方法及其应用于双极障碍和精神分裂症的跨诊断分类
IEEE transactions on medical imaging
|July 4, 2025
概括
这项研究引入了一种新的噪音标签学习方法,以提高精神障碍诊断的准确性. 该方法提高了使用神经成像数据对双相情绪障碍和精神分裂症等疾病的分类,克服了诊断偏见.
科学领域:
- 神经科学是一个神经科学.
- 人工智能的人工智能
- 精神病学是一个精神病学.
背景情况:
- 正确诊断精神障碍是具有挑战性的,因为主观的标准和重叠的症状之间的条件,如双相情感障碍 (BP) 和精神分裂症 (SZ).
- 临床诊断可能容易产生偏见或错误,影响研究和实践中使用的诊断标签的可靠性.
研究的目的:
- 通过解决杂的诊断标签,开发和验证一种新的计算方法,以提高精神障碍的诊断准确性.
- 利用神经成像数据和先进的机器学习技术,实现更强大的精神疾病的跨诊断分类.
主要方法:
- 提出了一种利用多个深度神经网络 (DNN) 的互惠多网络噪音标签学习 (MMNNLL) 方法.
- MMNNLL最大限度地提高了DNN之间的一致性,以识别和使用具有清洁和噪音标签的样品.
- 将该方法应用于BP和SZ患者的大脑功能连接数据,并与公共数据集 (CIFAR-10,PathMNIST) 进行验证.
主要成果:
- 在公开数据集上,MMNNLL在分类各种标签噪声类型和水平的独立测试数据方面表现出有效性.
- 该方法显著优于现有的最先进的噪音标签学习技术.
- 对BP和SZ数据的应用确定了两个生物型,具有较大的群体差异和比原始临床类别更好的分类准确性.
结论:
- 通过使用强大的噪音标签学习,MMNNLL方法有效地减轻精神障碍鼻科学的不准确性.
- 该方法促进了跨诊断分类,提供了一种更准确,更可靠的方法来分类精神疾病.
- 多网络合作和MMNNLL内部的竞争提高了诊断精度,特别是在处理复杂和可能错误的临床标签时.
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