右心室与左心室体积比率的预后值在三回中
Robert S Zhang1, Pablo Villar-Calle1, Lily Jin1
1Division of Cardiology, Weill Cornell Medicine, New York, New York, USA.
JACC. Advances
|July 4, 2025
概括
右心室与左心室体积比 (RV/LVvol) 是三回 (TR) 中死亡率的强有力的预测指标. 这个比率捕捉了常规指标错过的心室重塑,改善了风险评估.
科学领域:
- 心脏病学 心脏病学
- 心脏成像 - - 心脏成像
- 预测生物标志物 预测生物标志物
背景情况:
- 三体反 (TR) 与右心室 (RV) 重塑有关.
- 传统的RV指标可能无法完全捕捉TR中的双心室相互作用.
研究的目的:
- 评估TR患者的RV/LVvol比率的预后意义.
- 为了确定RV/LVvol比率是否提供了超越传统RV指数的增量预后价值.
主要方法:
- 对949名患有≥中度TR且接受心脏MRI的患者的回顾性分析.
- RV/LVvol比率以二分法和根据严重程度层进行评估.
- 通过社会保障死亡指数和电子医疗记录追踪全因死亡率.
主要成果:
- 在43.6%的患者中发现异常的RV/LVvol比率 (≥1.27).
- 异常的RV/LVvol比率独立预测死亡率的增加 (aHR:1.47,P=0.043).
- RV/LVvol比率显著改进了结合常规RV指标的预后模型.
结论:
- RV/LVvol比率是晚期TR患者死亡率的强有力的预测指标.
- 这一比率有效地识别了在标准RV评估中遗漏的心室重塑.
- RV/LVvol比率提高了TR患者的风险分层.
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