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Updated: Sep 16, 2025

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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药量计和数字双胞胎建模用于在晚期胃癌中适应性安排组合疗法

Michela Prunella1, Nicola Altini1, Rosalba D'Alessandro2

  • 1Department of Electrical and Information Engineering (DEI), Polytechnic University of Bari, BA, 70126, Italy.

Computer methods and programs in biomedicine
|July 4, 2025
PubMed
概括

这项研究开发了一种药量计模型,以优化组合癌症治疗,找到一种新的疗法,可以减少33%的细胞毒药物使用,同时保持无进展生存 (PFS-2). 另一种疗法在标准剂量下改善了PFS-2的10%以上.

关键词:
适应性的药物治疗方案晚期的胃癌是什么?癌症数字双胞胎 癌症数字双胞胎药理动力学药理动力学建模量化系统药理学 药理学治疗窗口的治疗窗口

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