治疗方法和在迷幻诱导精神病的疗效:一个系统的审查
Adi Sulstarova1, Luise Scheuerlein2, Silvia Monari3
1Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 2, Chemin du Petit-Bel-Air, Thônex CH-1226, Switzerland.
Asian journal of psychiatry
|July 4, 2025
概括
第二代抗精神病药物显示出治疗迷幻诱导精神病的前景,反应率高于旧药物. 需要进一步的研究来优化这种情况的治疗方案.
科学领域:
- 精神病学和药理学 精神病学和药理学
- 心理健康研究 心理健康研究
背景情况:
- 迷幻药越来越多地被使用,但可以在很小比例的用户中诱导精神病.
- 治疗迷幻诱导精神病的证据有限,需要进一步调查.
研究的目的:
- 系统地审查和分析迷幻诱导精神病的治疗选择.
- 确定有效的药理和非药理干预措施.
主要方法:
- 从研究开始到2024年8月,对研究进行符合PRISMA 2020标准的系统审查.
- 包括干预性,观察性研究,病例系列和病例报告.
- 对93例病例的人口,治疗和结果特征的分析.
主要成果:
- 第二代抗精神病药物 (91.3%的响应率) 比第一代药物 (27%的响应率) 更有效.
- 电疗法也显示出高响应率 (91%).
- 主要涉及的物质是LSD和MDMA;平均精神病持续时间为1.8周.
结论:
- 第二代抗精神病药似乎更有利于管理迷幻诱导的精神病.
- 主要来自病例报告的有限证据强调了需要优化治疗方案和进一步研究的需要.
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