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视神经外直径在创伤性视神经病变患者的预后:评估和预测效率

Yuxin Luo¹, Yuxing Jie¹, Keying Wu¹

¹Department of Otolaryngology-Head and Neck Surgery, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, People's Republic of China.

World neurosurgery

|July 4, 2025

概括

视神经外直径 (ONSD3) 可以预测创伤性视神经病变的视觉预后. 更小的ONSD3测量表明更好的结果,有助于治疗决策.

科学领域:

眼科医生眼科眼科
神经学神经学
放射学放射学是一门学科.

背景情况:

创伤性视神经病变 (TON) 在预测视觉结果方面具有重大挑战.
准确的预后对于指导TON患者的治疗策略至关重要.

研究的目的:

评估视神经外直径 (ONSD) 作为TON患者视觉预后的预测指标.
评估ONSD测量在预测治疗反应和视力恢复方面的有效性.

主要方法:

研究了一组22名被诊断患有TON的患者.
在治疗前使用CT扫描测量视神经外直径在地球背后3毫米 (ONSD3).
使用统计分析,包括ROC曲线和决策曲线分析,以确定预测准确度.

主要成果:

在接受有效治疗的患者中,ONSD3明显低于接受无效治疗的患者 (P < 0.05).
ONSD3显示出高预测效率 (AUC=0.893) 的预后,ONSD3 ≤5.07毫米表明更高的良好的视力恢复的可能性 (灵敏度100%,特异性85.7%).
将ONSD3与初始视力敏度相结合,进一步提高了预测准确度 (AUC=0.929).

结论:

ONSD3是一个新的和有价值的指数,用于评估和预测创伤性视觉神经病变的视觉预后.
测量ONSD3,特别是与初始视力敏度相结合,为TON的患者管理提供了显著的好处.

关键词:

机器学习是机器学习.视神经外套的直径是预测预测预测预测创伤性视觉神经病变是一种创伤性视觉神经病变.

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