生产腹膜的营养:如何以及何时?
Ulla Lei Larsen1, John T Wren2, Christy Gilcrease3
1Research Unit for the Department of Anaesthesiology & Intensive Care, Odense University Hospital, University of Southern Denmark, Odense, Denmark.
Seminars in fetal & neonatal medicine
|July 4, 2025
概括
患有先天性隔膜 (CDH) 的婴儿通常会遇到营养问题,如营养不良和生长失败. 本综述涉及养策略和生长目标,以改善这些脆弱婴儿的结果.
科学领域:
- 儿科手术 儿科手术
- 新生儿科学 新生儿科学
- 营养科学 营养科学
背景情况:
- 出生腹膜 (CDH) 的生存率有所提高,但仍然存在重大营养挑战.
- 患有CDH的婴儿容易发生生长不良,营养不良,GERD和口腔厌恶,通常需要住院后输液管养.
- 营养不良会对CDH幸存者的神经发育产生负面影响.
研究的目的:
- 审查当前的证据,并解决有关CDH婴儿营养管理的争议.
- 提供有关肠道和肠外营养目标,养策略和生长目标的指导.
- 讨论出院后的营养支持和家长的担忧.
主要方法:
- 文献综述和现有证据的综合对CDH婴儿的营养支持.
- 关于外科手术前肠道食的讨论,营养在ECMO中的作用,以及生长目标.
- 确定研究和临床实践当前的差距.
主要成果:
- 关于CDH婴儿最佳营养策略的证据有限,并且经常受到争议.
- 争议的关键领域包括肠道养的时间/方式,ECMO期间营养的作用和生长目标.
- 需要在婴儿的整个生命过程中制定标准化的营养护理指南.
结论:
- 优化营养支持对于改善CDH幸存者的神经发育结果至关重要.
- 需要进一步的研究,以建立基于证据的营养管理指南.
- 解决家长的担忧和提供一致的支持对于成功的长期结果至关重要.
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