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Updated: Sep 16, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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RASGRF融合的遗传和瘤特征

Sreya Das1,2,3, Daniel S Lenchner1,2,3, Ellen Jaeger4

  • 1Department of Internal Medicine, Section of Medical Oncology, Yale School of Medicine, New Haven, CT, USA.

NPJ precision oncology
|July 4, 2025
PubMed
概括

拉斯格尔夫融合是肺癌和胰腺癌等癌症中新发现的致癌驱动因素. 这些融合激活了RAS通路,并且可能是MAPK抑制剂的目标.

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