在津巴布韦的疟疾预防药物库存不足以及出生和孕产妇的结果
Abigail Chari1,2, Ronelle Burger3, Dieter von Fintel3,4
1Research On Socioeconomic Policy, Department of Economics, Stellenbosch University, Stellenbosch, South Africa. abiechari@gmail.com.
BMC public health
|July 4, 2025
概括
津巴布韦的疟疾预防库存不足会对新生儿的平均出生体重产生负面影响,增加发育问题的风险. 确保持续的药物可用性对于孕产妇和婴儿健康结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 制药科学 制药科学
背景情况:
- 疟疾在津巴布韦不成比例地影响孕妇和新生儿,导致死亡率和不良健康结果.
- 由于潜在的长期健康后果,在这个脆弱群体中预防疟疾至关重要.
- 这项研究调查了疟疾预防药物库存不足与津巴布韦孕妇和新生儿健康状况之间的联系.
研究的目的:
- 检查疟疾预防药物库存不足与津巴布韦孕妇和新生儿健康状况之间的相关性.
- 确定药物可用性对出生体重和相关风险的影响.
主要方法:
- 利用卫生和儿童护理部有关疟疾预防药物库存 (2011-2015年) 的行政数据.
- 纳入了2015年津巴布韦人口与健康调查的数据.
- 采用普通最小平方和定量回归来估计缺货和健康结果之间的相关性.
主要成果:
- 在研究期间,疟疾预防药物库存量增加.
- 库存不足与新生儿的平均出生体重 (第50百分位数) 有显著的负相关性.
- 虽然与低出生体重无关,但缺货导致平均出生体重下降,增加发育障碍的风险.
结论:
- 确保在医疗保健设施中持续提供硫素/甲 (SP) 是至关重要的.
- 建议对制药和库存订购系统进行投资,以优先考虑疟疾预防.
- 改善药物可用性和药物坚持的策略是必要的,例如更频繁的设施访问.
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