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评估不同严重程度帕金森病患者的牙健康:一个横截面研究
Ziyu Ge1, Jing Chen2, Xinhui Chen3
1Department of General Dentistry, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
晚期帕金森病 (PD) 患者的口腔健康状况恶化,包括牙周问题和未经治疗的. 整合牙科护理对于有效管理PD至关重要.
科学领域:
- 神经学 神经学
- 口腔健康 口腔健康
- 公共卫生 公共卫生
背景情况:
- 帕金森病 (PD) 与牙问题的风险增加有关.
- 患PD患者的口腔健康状况因疾病严重程度而异.
研究的目的:
- 评估中国PD患者的牙损伤,口腔卫生和牙周健康状况.
- 使用标准化尺度将口腔健康与PD严重程度相关联.
主要方法:
- 424名PD患者使用MDS-UPDRS和修改后的Hoehn和Yahr尺度进行评估.
- 使用DMFT,CPITN和OHI-S指数评估牙状况.
- 回归分析确定了PD和牙科参数之间的关联.
主要成果:
- 晚期PD阶段与较差的牙周健康相关 (β=0.771,p<0.001).
- 运动障碍与更多未经治疗的 (β=0.066,p<0.001) 和较差的口腔卫生 (β=0.030,p<0.001) 相关.
- 增加的/吞困难与更多的牙相关 (rho=0.218,p<0.00019).
结论:
- 在晚期PD患者中观察到较差的口腔健康状况,独立于人口因素.
- 强调需要将口腔护理纳入帕金森病管理的必要性.
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