饮食模式和肺癌的几率:伊朗的一项大型病例对照研究
Farimah Dehghani1, Fatemeh Toorang2,3, Saba Narmcheshm4
1Cancer Research Center, Cancer Institute, Tehran University of Medical Science, Tehran, Iran.
BMC nutrition
|July 4, 2025
概括
富含水果和鱼类的pesco-素食饮食可能会增加患小细胞癌肺癌的风险. 其他饮食模式与肺癌风险没有显著关联.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 肺癌是全球癌症死亡的主要原因之一.
- 饮食习惯对肺癌风险的影响仍然不完全理解.
- 这项研究调查了伊朗的饮食模式和肺癌风险.
研究的目的:
- 评估不同饮食模式与患肺癌的可能性之间的关联.
- 为了确定可能影响肺癌风险的特定饮食习惯.
- 为预防肺癌提供对生活方式修改的见解.
主要方法:
- 一项大型病例对照研究 (IROPICAN) 涉及608例肺癌病例和3397例对照.
- 评估饮食摄入量使用经过验证的171项食物频率调查问卷.
- 因子分析确定了饮食模式;后勤回归分析了它们与肺癌风险的关联.
主要成果:
- 确定了三个主要的饮食模式:"Pesco素食"",动物和糖"",碳水化合物,脂肪和蛋".
- 较高的坚持"Pesco素食"模式 (富含水果,蔬菜,鱼类) 与小细胞癌的几率增加有显著关联 (OR=1.81,P=0.04).
- 在其他两种饮食模式与整体肺癌风险或其亚型之间没有发现显著的关联.
结论:
- 总体而言,饮食摄入量与肺癌风险没有显著关联.
- 坚持"Pesco素食"饮食模式可能与患小细胞癌的风险更高有关.
- 需要进一步的研究来证实这些发现并阐明涉及的机制.
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