一个全基因组研究吸烟对神经退行症的遗传和因果影响

相关实验视频

Updated: Sep 16, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

19.1K

Chaochao Chen1,2,3, Shouqiang Zhu1,2,3, Zhiying Zheng1,2,3

  • 11Department of Anesthesiology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, 321 Zhongshan Road Street, Gulou District, Nanjing, 210008, Jiangsu, China.

Journal of translational medicine
|July 4, 2025
PubMed
概括

开始吸烟和每天吸烟显著增加了阿尔茨海默病的风险. 相反,戒烟与帕金森病和ALS风险的降低有关,这突显了吸烟在神经退行过程中的复杂作用.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.肌缩性侧面硬化症 (AMLS) 是一种疾病.遗传相关性 遗传相关性门德尔的随机化神经退行性疾病的神经退行性疾病帕金森病是帕金森氏症的一种疾病.吸烟 吸烟 吸烟 吸烟

更多相关视频

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System06:07

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

Published on: October 22, 2020

6.8K
A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior06:59

A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior

Published on: May 21, 2020

4.2K

相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
14.4K
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
734
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
152
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
544