儿科人口的后感染性易怒肠综合征:中东国家首次数据
Sara Mina1, Sara Daher2, Sara Jamal Elddin3
1Department of Medical Laboratory Sciences, Faculty of Health Sciences, Beirut Arab University, Beirut, 11-5020, Lebanon. s.mina@bau.edu.lb.
BMC pediatrics
|July 4, 2025
概括
儿童的急性胃肠炎 (AGE) 可能导致感染后易发性肠综合征 (PI-IBS). 罗塔病毒导致严重的AGE,而寄生虫和细菌感染显示CRP水平较高,与PI-IBS发展相关.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 传染性疾病 传染性疾病
- 临床研究 临床研究
背景情况:
- 急性胃肠炎 (AGE) 是全球儿童住院和死亡的主要原因.
- 年龄被认为是患上感染后刺激性肠综合征 (PI-IBS) 的风险因素.
- 了解AGE病因和PI-IBS之间的联系对于儿科健康至关重要.
研究的目的:
- 为了将AGE的临床严重程度与特定的传染病原体相关联.
- 为了调查PI-IBS在北黎巴嫩儿童和青少年中发生的情况.
- 为了确定年龄增长后PI-IBS发展的潜在风险因素.
主要方法:
- 纳入了219名患有胃肠道疾病的儿科患者 (4-15岁).
- 分析了便样本的微生物病原体;使用维斯卡里尺度来评分AGE的严重程度.
- 用罗马四号标准和布里斯托尔便尺度监测患者PI-IBS的发展.
主要成果:
- 病毒病原体是最常见的 (26.9%),轮状病毒与严重的AGE (25.1%) 相关.
- 寄生虫和细菌AGE病例显示C反应蛋白 (CRP) 水平升高 (p=0.009).
- 13.24%的患者患上PI-IBS,主要是混合肠道习惯 (IBS-M).
结论:
- 这项研究提供了对黎巴嫩儿科人口PI-IBS发展的初步见解.
- 特定的AGE病因可能会影响PI-IBS风险和严重程度.
- 需要进一步的研究来阐明PI-IBS病原和预防策略.
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