慢性腰部疼痛患者和对照患者中患者报告结果的相关性
Spencer A Baker1, Kelsey A Clark2, Andrew K Gibbons1
1Department of Mechanical Engineering, Brigham Young University, Engineering Building, Provo, UT, 84602, USA.
BMC musculoskeletal disorders
|July 4, 2025
概括
患者报告的结果 (PROs) 与慢性腰部疼痛 (CLBP) 相相关,并且在传统和PROMIS PROs之间表现相似. CLBP调节了这些关系,表明了更有针对性的PRO开发的机会.
科学领域:
- 健康研究成果研究结果
- 生物医学信息学是生物医学信息学.
背景情况:
- 慢性腰部疼痛 (CLBP) 对个人和经济产生重大影响.
- 患者报告结果 (PROs) 评估CLBP中的健康和福祉.
- 不同的PRO类型之间存在相关性,以及传统和新型PROMIS PRO之间存在相关性.
研究的目的:
- 在患有CLBP和没有CLBP的人群中比较PRO相关性.
- 调查CLBP如何调节PRO关系.
- 确定影响PRO变异的潜在因素.
主要方法:
- 在35-65岁的成年人中比较遗留和PROMIS PROs (n=133) 和没有 (n=100) CLBP.
- 使用了Welch t测试和线性回归,考虑了CLBP.
- 进行探索性因子分析以确定潜在因素.
主要成果:
- 患有CLBP的人在大多数PRO中报告得分较低.
- 在治疗疼痛和残疾的 PROMIS 和传统 PRO 之间发现了强烈的相关性.
- 临床临床BP显著缓解了这些相关性; catastrophizing 疼痛和焦虑显示了中等相关性.
结论:
- 传统和PROMIS PRO显示了与CLBP相似的相关性表现.
- 潜在因素分析表明,有可能开发出更有针对性的PRO.
- 未来的PRO可以通过关注已识别的特征来更好地捕捉结果变异.
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