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喉感官神经病变咳与膜状声病变无关
Diego E Razura1,2, Tyler Gallagher2, Nyree Khachikyan3
1Department of Otolaryngology - Head & Neck Surgery, Mayo Clinic Arizona, Phoenix, Arizona, USA.
The Laryngoscope
|July 5, 2025
概括
喉感官神经病性咳 (LSNC) 很少与声病变有关. 慢性咳的持续时间似乎不会增加患上这些病变的风险.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
- 神经学 神经学
背景情况:
- 喉感官神经病性咳 (LSNC) 是一种由慢性咳所表现的异常疾病.
- 诊断可能具有挑战性,其与喉病理学的关联需要进一步调查.
研究的目的:
- 为了检查LSNC和膜性声 (VF) 病变之间的关联.
- 了解LSNC的临床表现和诊断挑战.
主要方法:
- 从2015年至2020年对119名患有慢性咳 (持续时间>8周) 的成年患者进行了回顾性审查.
- 分析包括喉视频强光镜,人口统计,咳严重程度指数 (CSI) 和咳持续时间.
- 统计分析涉及千平方测试和多变量后勤回归.
主要成果:
- 在44.2%的患者中诊断出LSNC. 大多数是女性 (66.4%) 和白人 (39.5%),平均年龄为59.8岁.
- 平均咳持续时间为5.8年,平均CSI为20.8. 大多数患者 (88.2%) 的喉检查正常.
- 无论是单变量还是多变量回归,都没有显示出咳持续时间和静脉瘤病变存在的显著关联 (p > 0.05).
结论:
- 在这个患者队列中,膜状声病变很少与LSNC有关.
- 在患有LSNC的患者中,慢性咳的持续时间可能不是发展声病变的重要风险因素.
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