肺动脉弹性和心室功能受损的胎儿与 tetralogy of Fallot 的胎儿
Yushan Liu1, Dan Zhou1, Yang Yang1
1Department of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, Changsha, China.
概括
胎儿四重法洛特病 (TOF) 显著降低了主要肺动脉 (MPA) 的压力,表明弹性下降. 患有TOF的胎儿的右心室功能受损与这种减少的MPA菌株有关.
科学领域:
- 心脏病学 心脏病学
- 胎儿医学 胎儿医学
- 儿童心脏病学 儿童心脏病学
背景情况:
- 费洛特四病 (TOF) 是一种先天性心脏缺陷,影响肺动脉发育.
- 评估TOF胎儿的肺动脉弹性对于了解疾病进展至关重要.
研究的目的:
- 为了比较主要肺动脉 (MPA) 和其分支在TOF胎儿与正常胎儿的弹性,测量为应变.
- 调查MPA菌株与TOF胎儿右心室 (RV) 功能之间的相关性.
主要方法:
- 对42名TOF胎儿和84名对照胎儿进行前性研究.
- 用于测量肺动脉直径 (抽缩和放缩) 的M模式回声心脏学.
- 肺动脉应变用100 × (Dmax - Dmin) /Dmin.公式计算出来.
主要成果:
- 与对照人群相比,TOF胎儿的MPA菌株显著较低 (P < .05).
- 严重的TOF病例显示MPA菌株明显低于轻度至中度病例 (P < .05).
- 在TOF的胎儿中观察到VR缩和透缩功能受损,与MPA菌株负相关.
结论:
- 胎儿TOF与明显减少的MPA菌株有关,特别是在第二和第三季度.
- TOF胎儿的RV功能受损显而易见,与减少的MPA菌株直接相关.
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