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卡达摩宁通过AhR/Nrf2/NLRP3信号通路缓解LPS诱导的断奶小猪的肠道炎症

Xiwen Hu1, Yi Fang1, Yalei Zhang1

  • 1Institute of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China.

International immunopharmacology
|July 5, 2025
PubMed
概括

卡达摩宁 (CDN) 保护断奶小猪免受来自免疫应激的肠道损伤. 它通过激活AhR/Nrf2/NLRP3通路来增强肠道屏障功能并减少炎症.

关键词:
在 AhR/Nrf2/NLRP3 信号通路中.卡尔达蒙尼尼是一种卡尔达蒙尼.在IPEC-J2细胞中.肠道屏障 肠道屏障 肠道屏障皮格莱特小猪肉,就是一个小猪肉.

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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The heterodimer of NF-κB...