关于与肥胖相关的脏疾病的S.E.N.,SLANH和SEEDO共识报告:关于新分类的建议
Jorge Rico-Fontalvo1, Andreea Ciudin2, Ricardo Correa-Rotter3
1Nephrology Department, Universidad Simón Bolívar, Barranquilla, Colombia; Colombian Association of Nephrology (ASOCOLNEF), Bogotá, Colombia.
Kidney international
|July 5, 2025
概括
与肥胖相关的慢性病 (Ob-CKD) 对所有CKD阶段的患者产生影响. 一个新的共识统一了Ob-CKD的分类和管理,包括多学科的肥胖治疗和基于incretin的疗法.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 肥胖医学 肥胖医学
- 心血管医学 心血管医学
背景情况:
- 与肥胖相关的慢性病 (Ob-CKD) 在慢性病 (CKD) 患者中呈现出各种表现.
- 这些包括从高过到晚期损伤,透析和移植后情景的各个阶段.
- 目前的管理层缺乏统一的命名法和全面的战略.
研究的目的:
- 根据脏变化和CKD阶段,提出对Ob-CKD的统一分类.
- 建立一个标准化命名体系,以改善 Ob-CKD 管理.
- 概述当前和新兴的 Ob-CKD 治疗策略.
主要方法:
- 由领先的脏病学和肥胖学会 (S.E.N.,SLANH,SEEDO) 开发的一份共识报告.
- 审查和整合对Ob-CKD病理学和临床表现现现有的知识.
- 确定新分类系统的关键元素.
主要成果:
- 一个对Ob-CKD的拟议分类系统,按脏病理和CKD阶段 (CKD,透析,移植) 分类.
- 承认需要在CKD患者中进行多学科肥胖管理.
- 突出基于英克雷丁的疗法在减肥和心脏脏方面的潜力.
结论:
- 该共识为分类和管理Ob-CKD提供了一个统一的框架.
- 有效的 Ob-CKD 管理需要多学科的方法,包括生活方式,药物治疗和潜在的减肥手术.
- 基于因克雷的疗法代表了治疗Ob-CKD的有希望的新途径,改善了结果并降低了心血管死亡率.
相关概念视频
Nephrotic Syndrome II : Assessment and Medical Management
24
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
24
Nephrotic Syndrome I : Introduction
31
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
31
Chronic Kidney Disease I: Introduction
76
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
76
Chronic Kidney Disease III: Interprofessional Care
82
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
82
External Anatomy of the Kidney
1.7K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.7K
Chronic Kidney Disease II: Clinical Manifestations
104
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
104


