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Updated: Sep 16, 2025

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
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In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity

Published on: January 29, 2018

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SUMOylation不是HSF1在压力保护和事务激活中的作用的先决条件

Miroslav Bardelcik1,2, Oliver Simoncik1,3, Kristina Bednarova1,3

  • 1Research Centre for Applied Molecular Oncology (RECAMO), Masaryk Memorial Cancer Institute, Zluty kopec 7, Brno, 65653, Czech Republic.

Scientific reports
|July 5, 2025
PubMed
概括

在早期热冲击反应期间,SUMOylation不会影响热冲击因子1 (HSF1) 的活性. 这表明向HSF1稳定性,而不是SUMOylation,可能会改善Hsp90抑制剂癌症疗法.

关键词:
癌症 癌症 癌症 癌症在HSF1中,它是HSF1.热冲击反应热冲击反应这就是SUMOylation的作用.压力 压力 压力 压力副总结 副总结 副总结

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