花提取物装饰的纳米颗粒对食源性病原体的抗菌潜力
Nizar Fathima Mohamed Yunus Saleem1, Ranjani Soundhararajan1, Hemalatha Srinivasan2
1School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Chennai, 600048, India.
Discover nano
|July 5, 2025
概括
使用Moringa oleifera花合成的环保银纳米颗粒有效地对抗食物传播的病原体,并减少生物膜的形成. 这种可持续的创新支持食品安全和健康,与联合国可持续发展目标保持一致.
科学领域:
- 绿色合成和纳米技术
- 食品安全和微生物学
- 可持续发展和创新 可持续发展和创新
背景情况:
- 微生物污染导致食物腐烂和食源性疾病.
- 化学合成的纳米粒子对环境构成风险.
- 环保替代品对于可持续的食品安全至关重要.
研究的目的:
- 合成Moringa oleifera花中介的银纳米颗粒 (Mo-AgNPs). 通过花中介的银纳米颗粒.
- 评估Mo-AgNPs对食源性病原体的疗效.
- 研究Mo-AgNPs在食品包装应用中的潜力.
主要方法:
- 绿色合成Mo-AgNPs使用Moringa oleifera花提取物.
- 使用分析技术对Mo-AgNP进行表征.
- 抗菌试验 (井扩散,MIC,MBC) 和生物膜抑制试验.
- 在基分子对接研究中.
- 使用种子发芽和Artemia nauplii的毒性评估.
主要成果:
- 合成的Mo-AgNP的粒子大小为12.73nm.
- 在3.125微克/毫升和50微克/毫升的度下有效抑制和杀死食源性病原体.
- 显著减少细菌生物膜的形成.
- 分子对接确定了植物化合物 (埃拉基酸,Quercetin) 与细菌毒性蛋白的强有力的结合.
- 在较高度下,Mo-AgNPs显示植物生长效益和对Artemia nauplii的毒性.
结论:
- 合成的Mo-AgNPs对食品传播病原体具有显著的抗菌活性.
- Mo-AgNPs有效地抑制生物膜的形成,这对食品安全至关重要.
- 该研究支持使用Mo-AgNPs开发可持续食品包装以延长保质期.
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