相关实验视频
Updated: Sep 8, 2025

03:36
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
528
日本食道癌综合登记,2016年
Yasue Kimura1, Akihiko Okamura2, Masashi Takeuchi3
1Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan.
概括
这项研究分析了日本9,593例食道癌症病例,显示5年生存率因治疗而异. oesophagectomy 显示特定阶段的生存率有所改善,突出显示了治疗对食道癌症结果的影响.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 日本食道学会 (JES) 收集了2016年接受治疗的食道癌患者的数据.
- 这一数据集包括日本各地的患者特征,治疗方法和结果.
研究的目的:
- 分析日本食道癌患者的特征,治疗方法和结果.
- 为了提供对各种食道癌的不同阶段和类型的治疗疗效和生存率的见解.
主要方法:
- 分析了2016年在347个日本机构注册的9593例食道癌症病例.
- 使用了国家临床数据库,并遵循日本食道癌分类第11版 (JES) 和TNM分类第8版 (UICC) 进行分期.
主要成果:
- 状细胞癌和腺癌分别占病例的87.5%和7.2%.
- 五年生存率:内切除 (89%),食管切除 (59%),并发化疗 (36%),单独放射治疗 (26%).
- 在4,988例食道切除术中,57.7%进行了微创性食道切除术 (胸腔镜),存活率与JES分期相关.
结论:
- 该研究提供了对食道癌治疗和日本的结果的全面概述.
- 这些发现旨在提高食道癌的诊断和治疗策略.
相关概念视频
Barrett Esophagus-II: Clinical Manifestations and Management
290
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
290
Esophagus
1.3K
The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
1.3K
Barrett Esophagus-I: Introduction
197
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
197
Esophageal Strictures-II: Clinical Features and Management
155
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
155
Esophageal Varices-II: Clinical Features and Management
133
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
133
Esophageal Varices-I: Introduction
324
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
324

