重新评估现代时代艾滋病毒状况与手术后并发症之间的关联
Michael Guo1, Michael Budu2, Jason Trigg2
1Department of Surgery, St. Paul's Hospital & University of British Columbia, Vancouver, BC, Canada.
American journal of surgery
|July 6, 2025
概括
艾滋病毒 (人类免疫缺陷病毒) 感染者不会面临更高的手术感染或伤口并发症风险. 然而,收入援助和药物使用史等社会经济因素与这些患者感染风险增加有关.
科学领域:
- 手术成果研究的研究结果.
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- 现代艾滋病毒治疗显著改善了结果,挑战了以前关于增加外科手术期间死亡率的概念.
- 这项研究解决了重新评估艾滋病毒感染者 (PWH) 手术风险的必要性.
研究的目的:
- 为了比较经过整体手术的PWH和非PWH个体之间的术后感染和伤口并发症的可能性.
- 确定影响PWH手术结果的特定因素.
主要方法:
- 在不列颠哥伦比亚省 (BC) 艾滋病毒治疗数据库和医院行政记录 (2008-2020) 之间进行了数据链接.
- 接受整体手术的艾滋病毒感染者 (PWH) 与非PWH对照进行了匹配.
- 使用ICD-9/10代码识别了30天内的术后感染和伤口并发症.
主要成果:
- 艾滋病毒状况与术后感染 (OR:0.95) 或伤口并发症 (OR:1.07) 的增加几率没有显著关联.
- 然而,接受收入援助的PWH (OR: 1.57),有物质使用障碍 (OR: 1.38) 或有IV药物使用史 (OR: 2.90) 的PWH显示术后感染的几率更高.
结论:
- 仅仅艾滋病毒状况本身并不是增加术后感染或伤口并发症的重要预测因素.
- 社会经济因素,包括收入援助和药物使用史,是PWH手术感染风险的关键决定因素.
相关概念视频
Factors Affecting the Risk of Infection
12.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.3K
Pneumonia III: Complications and Assessment
452
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
452
Peripheral Artery Disease V: Postoperative Nursing Management
28
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
28
Healthcare Associated Infections II: Preventive Measures
2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K
Sexually Transmitted Infections
421
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
421
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
180
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
180


