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Updated: Sep 16, 2025

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
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利科伊索夫拉A通过向CDK2-Cyclin E1轴介导的细胞周期过渡来抑制结直肠癌细胞的增殖

Jingwei Cui1, Hao Chen1, Yuru Chen2

  • 1Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing 210022, China.

Biochemical pharmacology
|July 6, 2025
PubMed
概括

利科伊索夫拉A (LA) 通过向循环素依赖激酶2 (CDK2) 有效地抑制结肠直肠癌 (CRC) 细胞生长. 这种天然化合物通过破坏CDK2-Cyclin E1复合体来阻止癌细胞分裂,为CRC提供了一个有前途的新治疗策略.

关键词:
细胞循环的细胞周期结肠直肠癌是一种癌症.循环素依赖的激酶2 2利科伊索夫拉A是一种利科伊索夫拉.器官类动物 器官类动物

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