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Updated: Sep 16, 2025

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取决于ubiquitination的LLGL2降解通过THBS3mRNA稳定驱动结肠直肠癌的进展

Jiayan Huang1,2, Tiantian Zhang1,2, Huimin Li1,2

  • 1State Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|July 7, 2025
PubMed
概括

致命的(2) 巨型幼虫蛋白质同源2 (LLGL2) 在结肠直肠癌 (CRC) 中起到瘤抑制作用. 由于LLGL2的枯竭,通过稳定血栓蛋白3 (THBS3) mRNA,抑制PI3K-Akt通路,促进CRC的进展.

关键词:
LLGL2 LLGL2 在线阅读这就是PI3K-Akt.这就是THBS3的特点.结肠直肠癌是什么意思这就是ubquitination.

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