一个核心结果为死产护理设置:国际共识研究研究
Danya Bakhbakhi1, Anna Davies1, Dimitrios Siassakos2
1Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
概括
一项共识性研究制定了对死产护理的核心结果,包括母亲的健康,父母的经验和婴儿的结果. 这一标准化套件旨在提高研究的一致性,减少死胎研究中的偏见.
科学领域:
- 围产儿医学 围产儿医学
- 临床试验方法论 临床试验方法论
- 患者报告的结果
背景情况:
- 死产护理研究缺乏标准化的结果指标.
- 不一致的结果报告阻碍了元分析和研究可比性.
- 需要一个核心成果集,以提高死产研究的质量和影响.
研究的目的:
- 开发一个基于共识的核心结果集 (COS) 对于死产护理.
- 建立标准化研究和临床试验的死亡产生的结果.
- 尽量减少结果报告偏见,提高死胎研究的可比性.
主要方法:
- 国际共识发展研究,涉及542个利益相关者.
- 使用修改后的Delphi方法和共识会议.
- 包括有生活经验的父母和医疗保健专业人员.
主要成果:
- 对所有死产护理研究的8个核心结果达成一致 (例如,母亲的并发症,父母的悲伤,心理健康).
- 确定了具体研究领域的11个额外结果 (例如,死亡原因,随后的怀孕,多胎).
- 结果包括母亲的健康,父母的经验,婴儿的结果,以及特定的死胎背景.
结论:
- 开发的核心成果集为死胎研究提供了一个标准化的框架.
- 实施可以减少结果报告偏差,并促进元分析.
- 旨在提高研究效率,减少死胎研究中的浪费.
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