痴呆症错觉的神经相关:一个范围审查
Adèle Gagnon1, Bryn H Manns1, Karina Atanasiu1
1McGill University, Quebec, Canada.
概括
这次范围审查确定了31个与痴呆症妄想相关的大脑区域. 虽然没有一个单一的区域连接得一致,但几个是主要大脑网络的一部分,为痴呆症症状提供了洞察力.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 妄想是痴呆症中普遍存在的重要症状.
- 了解这些妄想的神经支对于有效管理至关重要.
研究的目的:
- 进行范围审查,确定痴呆症错觉的神经相关性.
- 综合实验研究中关于与痴呆相关妄想相关的大脑区域的研究结果.
主要方法:
- 在2020年12月搜索主要数据库 (MEDLINE,EMBASE,Web of Science) 进行了关于妄想和痴呆症的研究.
- 包括18项已发表的研究,采用四种不同的实验方法.
- 使用标准化工具提取干预和研究特征.
主要成果:
- 确定了31个与痴呆症错觉相关的不同大脑区域.
- 在所有研究中,没有一个单一的大脑区域被一致确定.
- 一些涉及的地区属于默认模式网络,突出网络或中央执行网络.
结论:
- 痴呆症中错觉的神经相关性是广泛的,不局限于单一区域.
- 特定的大脑网络的参与表明了这些复杂症状背后的潜在机制.
- 需要进一步的研究来阐明这些网络在痴呆症妄想的表现中的确切作用.
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