灌木伤寒的流行病学特征和时空集群分析 - 中国,2006-2023年
Yao Qin1,2,3, Shijian Zhou1, Qi Wang2,3
1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China.
China CDC weekly
|July 7, 2025
概括
中国的草风发病率大幅上升,呈现出明显的流行阶段和时空模式. 针对性的控制措施对于受影响地区来说至关重要,以管理这种重新出现的公共卫生威胁.
科学领域:
- 流行病学 流行病学
- 载体传播疾病 载体传播疾病
- 公共卫生 公共卫生
背景情况:
- 由携带Orientia tsutsugamushi的受感染小传播的伤风,是中国日益严重的公共卫生问题.
- 近年来,病例有所增加,并扩展到新的地区.
研究的目的:
- 分析从2006年到2023年的中国灌木伤寒的时空流行病学.
- 确定针对性干预的趋势,模式和高风险区域.
主要方法:
- 利用来自中国疾病控制和预防信息系统 (CISDCP) 的数据.
- 使用Joinpoint软件进行趋势分析和SaTScan/ArcGIS用于空间集群识别.
- 统计分析包括曼-惠特尼U测试,科克兰-阿米塔奇测试和二进制物流回归.
主要成果:
- 在2006年至2023年期间,草伤寒发病率从0.095/100,000上升到2.357/100,000,观察到三个不同的流行阶段.
- 在45岁以上的个体中,病例的比例增加,并确定了三个季节性模式 (夏季,秋季,夏季-秋季).
- 一个主要的集群在云南省被确定,地理扩张到中国中部和北部.
结论:
- 中国的草伤寒发病率大幅增加,达到峰值平原阶段.
- 这种疾病表现出明显的时空分布特征.
- 受影响地区需要采取有针对性的控制措施,以减轻灌木伤寒的影响.
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