身体活动作为沙特阿拉伯胃食道逆流病的可修改风险因素:系统性审查和元分析
Abdulrahman M Albeshry1, Saud Feaz Althobaiti2, Salem Almerri3
1Family and Community Medicine, Faculty of Medicine, University of Jeddah, Jeddah, SAU.
Cureus
|July 7, 2025
概括
低体力活动与胃食道逆流症 (GERD) 的更高风险有关. 参与定期的体力活动 (PA) 可能是防止沙特阿拉伯GERD的关键策略.
科学领域:
- 胃肠病学和公共卫生
- 非传染性疾病的流行病学
背景情况:
- 胃食道逆流性疾病 (GERD) 是一种普遍影响生活质量的疾病.
- 身体活动 (PA) 越来越多地被认为是其在预防GERD方面的潜在作用.
研究的目的:
- 系统地审查和元分析沙特阿拉伯体育活动和GERD之间的关联.
- 为了确定GERD的综合患病率和与较低的体力活动水平相关的风险.
主要方法:
- 来自沙特阿拉伯的横截面和准实验性研究 (2015-2024) 的系统审查和元分析.
- 搜索了多个数据库,包括PubMed,Scopus和区域图书馆.
- 使用纽卡斯尔-太华尺度评估研究质量,并使用MetaXL与随机效应模型进行元分析.
主要成果:
- 在250项研究中的6183名参与者中,GERD的综合患病率为35% (95% CI:24-47%).
- 较低的体力活动水平与患有GERD的可能性增加了22% (合并OR=1.22,95%CI:1.05-1.42).
- 在各个研究中观察到很高的异质性 (I2 = 99%,p < 0.001).
结论:
- 低体力活动是沙特阿拉伯人口中GERD的重要危险因素.
- 身体活动显示出作为减少GERD发病率的初级预防策略的潜力.
- 需要进一步的研究来阐明这种关联背后的机制.
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