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针对C3d的补充抑制剂,以纠正aHUS患者的补充失调

Valeria Guaschino1, Donata Santarsiero1, Sara Gastoldi1

  • 1Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Clinical Research Center for Rare Diseases Aldo e Cele Daccò and Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.

Frontiers in immunology
|July 7, 2025
PubMed
概括

针对非典型的血溶性尿素性综合征 (aHUS) 的新向疗法显示出有前途. 这些新型的补充抑制剂,局部化到受影响的细胞,有效地阻止补充激活,并防止血栓形成,没有系统性免疫抑制.

关键词:
一个房子的房子.补充抑制剂是一种补充抑制剂.互补系统是互补的系统.内皮细胞 (EC) 是一个内皮细胞.形成了血栓的形成.

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