在一般人群中早期青少年中形态的流行:基于人口的研究 (R世代)
Delong Chen1,2, Fleur Boel1,2, Suzanne de Vos-Jakobs1,3
1Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Arthritis care & research
|July 7, 2025
概括
关节骨关节炎的危险因素是钉形态,影响荷兰3.1%的早期青少年. 这种患病率在男性和女性中都是相似的,这表明早期干预的可能性.
科学领域:
- 整形外科和运动医学
- 发育生物学 发展生物学
- 放射学 放射学是一门学科.
背景情况:
- 形态,关节的骨异常,与股骨支骨塞综合征 (FAIS) 有关,并可能使个体易患关节炎 (OA).
- 子形态的发育期尚不清楚,青春期早期可能是其形成的时间.
- 缺乏有关形态在早期青少年群体中患病率的数据.
研究的目的:
- 确定荷兰早期青少年的一般人群中形态的患病率.
- 为了调查基于出生时分配的性别在这个年龄组的形态的分布.
主要方法:
- 利用了来自荷兰鹿特丹R世代前性队列研究的数据.
- 包括3986名年龄在13岁左右的青少年,他们接受了全身和部双能量X射线吸收仪 (DXA).
- 钉子形态是由40°以上的横向中心边缘角度 (LCEA) 定义的,自动从部轮地标测量.
主要成果:
- 在3,986名参与者中,形状的总体患病率为3.1% (95% CI 2.6% - 3.6%).
- 性别之间的患病率是可比的:男性3.0% (95% CI 2.2% - 3.7%) 和女性3.3% (95% CI 2.5% - 4.0%).
- 该研究的平均年龄为13.5岁,其中46.8%的参与者是男性.
结论:
- 在荷兰,3.1%的早期青少年中存在形态,没有显著的性别差异.
- 这些发现凸显了青春期早期识别和干预的潜力.
- 了解患病率可以为开发针对FAIS和部OA的预防策略提供信息.
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