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Updated: Sep 16, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

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一个分析管道,从瘤衍生的RNA测序数据中获得可靠的遗传祖先估计

Courtney E Johnson1, Ximing Ran2, Julia Wrobel2

  • 1Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
|July 7, 2025
PubMed
概括

来自瘤组织的RNA测序 (RNA-seq) 可以在缺少生殖基因DNA时估计全球遗传祖先. 这种方法在癌症研究中非常有效,特别是对于上皮卵巢癌 (EOC) 研究.

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Comparative Lesions Analysis Through a Targeted Sequencing Approach08:16

Comparative Lesions Analysis Through a Targeted Sequencing Approach

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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