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Updated: Sep 16, 2025

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脂肪组织在肥胖中含有致病性T细胞,这些T细胞会加剧炎症性关节炎

Heather J Faust1, Margaret H Chang1,2, A Helena Jonsson1,3

  • 1Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

The Journal of experimental medicine
|July 7, 2025
PubMed
概括

肥胖会通过内脏脂肪组织 (VAT) 中的T细胞恶化炎症性关节炎. 在T细胞中的干扰素α信号驱动这种免疫反应,增加肥胖个体关节炎的严重程度.

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