长期COVID综合征:探索治疗方法来管理和克服持续的症状
Dhrita Chatterjee1, Kousik Maparu2
1Pharmacology Division, Sanaka Education Trusts Group of Institutions, Durgapur, Malandighi, 713212, India.
Inflammopharmacology
|July 7, 2025
概括
长期COVID (SARS-CoV-2感染的后急性后续) 影响了数以百万计的持续症状. 本综述探讨了其原因,影响和治疗方法,包括药物和康复,以更好地长期管理COVID-19.
科学领域:
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
- 神经学 神经学
- 心脏病学 心脏病学
- 心理健康 心理健康
背景情况:
- 长期COVID (SARS-CoV-2感染后急性后续,PASC) 影响10-35%的COVID-19幸存者,呈现持续的多系统症状.
- 病理生理学是复杂的,可能涉及免疫失调,炎症,内皮功能障碍,肠道失生症和病毒持续性.
研究的目的:
- 审查长期COVID的流行病学,危险因素和临床表现.
- 专注于长期COVID对心肺,神经和精神健康的影响.
- 检查长期COVID的当前和新兴治疗策略.
主要方法:
- 对长期COVID的流行病学数据,临床研究和治疗干预措施的文献综述.
- 对药理和非药理治疗方法的研究进行分析.
- 对正在进行的长期COVID疗法临床试验的审查.
主要成果:
- 长期COVID呈现出各种症状,包括疲劳,呼吸困难,认知障碍和情绪障碍.
- 心肺和神经系统受到显著影响.
- 目前正在探索多种治疗途径,包括抗炎药物,康复和像干细胞疗法这样的新方法.
结论:
- 了解长期COVID的机制和风险因素对于有效管理至关重要.
- 药理和非药理策略的结合显示出患者康复的前景.
- 进一步的研究和个性化治疗策略对于优化长期COVID护理至关重要.
更多相关视频
相关概念视频
Chronic Obstructive Pulmonary Disease-V: Management
2.7K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.7K
Cystic Fibrosis: Management
227
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
227
COPD: Management Using Bronchodilators and Corticosteroids
322
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
322
Classification of Illness
8.0K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
8.0K
Chronic Pancreatitis II: Collaborative Care
131
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
131
COPD: Pathogenesis and Clinical Features
533
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
533


