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Updated: Sep 16, 2025

Acute Kidney Injury Model Induced by Cisplatin in Adult Zebrafish
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与非选择性环氧基因酶抑制剂相比,切莱科西布对西斯普拉丁诱导的毒性具有较小的加重作用:一项回顾性多机构研究

Keisuke Okamoto1, Yoshitaka Saito2, Kenta Takahashi3

  • 1Faculty of Pharmaceutical Sciences, Laboratory of Clinical Pharmaceutics and Therapeutics, Division of Pharmasciences, Hokkaido University, Kita-12-Jo, Nishi-6-Chome, Kita-Ku, Sapporo, 060-0812, Japan.

International journal of clinical oncology
|July 7, 2025
PubMed
概括

与非选择性COX抑制剂相比,切莱科西布在肺癌患者中显著降低了西斯普拉丁诱导的毒性 (CIN). 这表明,在化疗期间预防损伤时,塞莱科克西布是一种更安全的选择.

关键词:
切莱科克西布 (Celecoxib) 是一种药物.西斯普拉丁 (Cisplatin) 是一种诱导性毒性诱导性毒性洛克索普罗芬 (Loxoprofen) 是一种一种纳普洛克森 (Naproxen) 是一种药物.非选择性的环氧化原酶抑制剂非类固醇抗炎药物 非类固醇抗炎药物

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