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Updated: Sep 16, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Published on: July 25, 2013

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AFToolkit:一种用于分子建模蛋白质的框架,具有由AlphaFold衍生的表示形式

Maria Sindeeva1, Alexander Telepov1, Nikita Ivanisenko1

  • 1Bioinformatics Group, AIRI, Moscow 121170, Russia.

Briefings in bioinformatics
|July 7, 2025
PubMed
概括

本研究提出了一种修改的AlphaFold2 (AF2) 推断方法,以更好地预测突变如何影响蛋白质稳定性和结构. 新的方法,AFToolkit,提高了蛋白质工程能力,而不需要广泛的再培训.

关键词:
蛋白质工程工程 蛋白质工程蛋白质的稳定性 蛋白质的稳定性蛋白质蛋白质结合亲和力 亲和力

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