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在金沙萨,刚果民主共和国的关键人群中,从护理和阻碍到PrEP使用的障碍:多种方法研究

Natalia Zotova¹, Alisho Shongo², Patricia Lelo³

¹Division of General Internal Medicine, Department of Medicine, Albert Einstein College of Medicine, 3300 Kossuth Ave, Bronx, NY, 10467, USA. natalia.zotova@einsteinmed.edu.

AIDS and behavior

|July 7, 2025

概括

在刚果民主共和国,在女性性工作者和与男性发生性关系的男性中观察到高比例的HIV预防药 (PrEP) 停用. 耻辱感,副作用和每日剂量挑战阻碍了对预防艾滋病毒的一致性PrEP使用.

科学领域:

公共卫生公共卫生
传染病流行病学传染病流行病学
艾滋病毒预防研究预防研究

背景情况:

女性性工作者 (FSW) 和与男性发生性关系的男性 (MSM) 在全球面临不成比例的高艾滋病毒感染率.
口服暴露前预防 (PrEP) 是一种关键的艾滋病毒预防工具,在刚果民主共和国 (DRC) 等非洲国家越来越多.
关于影响刚果民主共和国关键人口接受和持续使用PrEP的因素的数据有限.

研究的目的:

检查金沙萨,刚果民主共和国的FSW和MSM中PrEP消耗模式.
确定这些关键人群持续参与PrEP服务的障碍.
为改善在高负担环境中改善PrEP遵守和有效性的策略提供信息.

主要方法:

一种多种方法研究,结合了程序数据,临床记录和定性访谈.
后勤回归分析以确定与PrEP消耗相关的因素.
对定性数据进行主题分析,以探索PrEP参与的障碍.

主要成果:

在2019-2021年期间,只有24%符合条件的FSW和MSM在2019-2021年期间启动了PrEP.
观察到高消耗率:33%的FSW和26%的MSM在1个月内损失;78%的FSW和87%的MSM在3个月内损失.
主要障碍包括耻辱感,副作用,不喜欢每日剂量,以及对关键人群的服务不足.

结论:

在刚果民主共和国金沙萨的FSW和MSM中发生了显著的PrEP消耗,限制了其对公共健康的影响.
解决耻辱感,副作用问题和剂量方便对于改善PrEP参与至关重要.
需要加强消息传递和定制服务,以支持在艾滋病毒风险关键人群中持续使用PrEP.

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