Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

1.6K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
1.6K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

4.5K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
4.5K
Introduction to Lymphatic and Immune System01:22

Introduction to Lymphatic and Immune System

8.2K
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
8.2K
Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

3.6K
The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
3.6K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

5.3K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
5.3K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

3.8K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
3.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Modulation of the immunogenic landscape in colorectal cancer by mitochondrial methylation-controlled J protein.

Molecular biomedicine·2026
Same author

Editorial: Innovative insights into pattern recognition and signaling in innate immunity.

Frontiers in immunology·2026
Same author

Editorial: Metabolism and tumor microenvironment nexus in neuro-oncology.

Frontiers in immunology·2026
Same author

Editorial: Innate and adaptive immunity in normal and adverse pregnancy.

Frontiers in immunology·2026
Same author

Molecular detection and phylogenetic characterization of pathogenic and endosymbiont microorganisms in Hyalomma ticks collected from livestock.

Parasites & vectors·2026
Same author

Expression of Properdin, the positive regulator of the Complement Alternative Pathway, at the fetal-maternal interface in Preeclampsia.

Frontiers in immunology·2026
Same journal

Mammalian Respiratory Chain Complex Assemblies and Their Links to Mitochondria Stress-Induced Human Diseases.

Advances in experimental medicine and biology·2026
Same journal

Enzyme Assemblies in Nucleotide Metabolism: Structure, Regulation, and Disease Implications.

Advances in experimental medicine and biology·2026
Same journal

The Pyruvate Dehydrogenase Complex: A 90-Year-Old Enigma Shaping the Future of Structural Enzymology.

Advances in experimental medicine and biology·2026
Same journal

Regulation of the Anti-termination RNA Transcription Complex by Lon-Mediated Lambda N Degradation.

Advances in experimental medicine and biology·2026
Same journal

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and Outside of the Nucleus.

Advances in experimental medicine and biology·2026
Same journal

Dynamic Assemblies in Genome Maintenance.

Advances in experimental medicine and biology·2026
查看所有相关文章

相关实验视频

Updated: Sep 16, 2025

Isolation of Group 2 Innate Lymphoid Cells from Mouse Nasal Mucosa to Detect the Expression of CD226
08:30

Isolation of Group 2 Innate Lymphoid Cells from Mouse Nasal Mucosa to Detect the Expression of CD226

Published on: May 10, 2022

2.0K

天生的淋巴细胞天生的淋巴细胞.

Ann Mary Joseph1, Hadida Yasmin2, Uday Kishore3,4

  • 1Department of Veterinary Medicine (CAVM), United Arab Emirates University, Al Ain, United Arab Emirates. ann_m@uaeu.ac.ae.

Advances in experimental medicine and biology
|July 7, 2025
PubMed
概括
此摘要是机器生成的。

天生的淋巴细胞 (ILC) 是关键的免疫细胞,维护常态稳定并对抗病原体. 它们的可塑性为癌症和自身免疫性疾病等疾病提供了治疗潜力.

更多相关视频

Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells
08:22

Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells

Published on: March 23, 2022

5.8K
Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations
10:23

Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations

Published on: January 19, 2017

11.1K

相关实验视频

Last Updated: Sep 16, 2025

Isolation of Group 2 Innate Lymphoid Cells from Mouse Nasal Mucosa to Detect the Expression of CD226
08:30

Isolation of Group 2 Innate Lymphoid Cells from Mouse Nasal Mucosa to Detect the Expression of CD226

Published on: May 10, 2022

2.0K
Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells
08:22

Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells

Published on: March 23, 2022

5.8K
Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations
10:23

Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations

Published on: January 19, 2017

11.1K

科学领域:

  • 免疫学 免疫学 免疫学
  • 细胞生物学 细胞生物学

背景情况:

  • 天生的淋巴细胞 (ILC) 是缺乏抗原特异性受体的必不可少的免疫细胞,作为CD4+ T辅助细胞的天生的对应物.
  • 它们在免疫稳定,组织修复和病原体防御中起着至关重要的作用.

研究的目的:

  • 根据细胞因子生产和转录因子,检查ILCs在ILC1,ILC2和ILC3子集中的分类.
  • 探索ILCs的基本特征,异质性和可塑性.
  • 审查ILC在各种生理和病理过程中的作用,包括免疫障碍和癌症.

主要方法:

  • 审查有关ILC分类和功能的当前研究.
  • 基于细胞因子和转录因子的ILC子集 (ILC1,ILC2,ILC3) 的分析.
  • 检查ILC参与健康和疾病状态的研究.

主要成果:

  • ILCs被分为具有明显特征的ILC1,ILC2和ILC3子集.
  • ILC的可塑性允许适应环境线索,影响各种生理和病理过程.
  • ILCs的失调与组织修复,炎症,喘,过敏,癌症和自身免疫性疾病有关.

结论:

  • 了解ILC可塑性是开发一系列疾病新型治疗干预措施的关键.
  • ILCs在癌症中表现出双重作用,可能促进或抑制瘤生长.
  • ILCs是健康和疾病的关键参与者,具有显著的治疗可能性.