Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

5.3K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
5.3K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

931
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
931
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

7.3K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
7.3K
Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

3.6K
The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
3.6K
What is the Immune System?01:38

What is the Immune System?

116.8K
Overview
116.8K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

73.5K
Overview
73.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

On-Cell Detection of Polysaccharide One-Bond <sup>1</sup>J<sub>CH</sub> Couplings by Proton-Detected Solid-State NMR.

Journal of the American Chemical Society·2026
Same author

Antifungal prophylaxis in influenza-associated pulmonary aspergillosis: addressing persistent challenges.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same author

Innovation in antifungal therapy.

EMBO molecular medicine·2026
Same author

Genotype-Phenotype Relationships in Azole-Resistant <i>Aspergillus</i>: Two Sides of the Same Coin.

Journal of fungi (Basel, Switzerland)·2026
Same author

Bronchoalveolar Lavage Fluid Collection in Invasive Pulmonary Aspergillosis Murine Model for Downstream Proteomic Analysis.

Methods in molecular biology (Clifton, N.J.)·2026
Same author

Aspergillus fumigatus Cell Wall: Current Advances in Structural Elucidation Methods.

Methods in molecular biology (Clifton, N.J.)·2026

相关实验视频

Updated: Sep 16, 2025

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

10.1K

抗真菌天生的免疫 抗真菌天生的免疫

Sarah Sze Wah Wong1, Sarah Dellière1,2, Mathieu Lepas1

  • 1Institut Pasteur, Université de Paris, Molecular Mycology Unit, UMR2000, CNRS, Paris, France.

Advances in experimental medicine and biology
|July 7, 2025
PubMed
概括

人的天生的免疫系统保护人免受真菌感染. 研究探讨了免疫防御,真菌毒性和免疫治疗策略,以对抗日益增长的耐药性和侵入性真菌病.

更多相关视频

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
12:29

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus

Published on: April 19, 2017

10.4K
Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy
09:04

Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy

Published on: July 9, 2014

11.6K

相关实验视频

Last Updated: Sep 16, 2025

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

10.1K
Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
12:29

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus

Published on: April 19, 2017

10.4K
Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy
09:04

Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy

Published on: July 9, 2014

11.6K

科学领域:

  • 免疫学 免疫学 免疫学
  • 菌类学 菌类学是指菌类学.
  • 传染性疾病 传染性疾病

背景情况:

  • 菌类在人体表面很常见,但由于天生的免疫力,感染很少发生.
  • 免疫受损的个体面临表面到危及生命的真菌疾病的风险.
  • 抗真菌药物耐药性的增加需要新的治疗方法,如免疫疗法.

研究的目的:

  • 审查与生俱来的免疫系统对抗真菌病原体的防御.
  • 检查由免疫系统抵消的真菌毒性机制.
  • 讨论基于天生的免疫的抗真菌治疗策略.

主要方法:

  • 审查关于宿主-病原体相互作用的现有文献.
  • 对先天免疫监测和反应机制的分析.
  • 对抗真菌实验性免疫疗法研究的评估.

主要成果:

  • 天生的免疫系统采用各种机制来控制真菌生长.
  • 菌具有可以克服宿主防御的毒性因子.
  • 免疫疗法看起来很有前途,但需要进一步的研究来临床应用.

结论:

  • 了解真菌病理生物学和宿主反应对于开发有效的抗真菌免疫疗法至关重要.
  • 天生的免疫力在预防和对抗真菌感染方面发挥着至关重要的作用.
  • 针对先天性免疫路径提供了对抗耐药性真菌病原体的潜在策略.