希夫基的双重功能:对金属离子的检测和广泛的抗菌作用
Afnan M Alnajeebi1, Alaa Shafie2, Abeer Alubaidi3
1Department of Biological Sciences, College of Science, University of Jeddah, Jeddah, Saudi Arabia. amalnajeebi@uj.edu.sa.
Journal of fluorescence
|July 7, 2025
概括
一个新型的Schiff基传感器 (SBS) 选择性地检测出高灵敏度的Ag+和Fe3+离子. 由此产生的金属复合物显示出增强的抗菌活性,在传感和医学方面具有潜在的应用.
科学领域:
- 协调化学 协调化学
- 分析化学 分析化学
- 材料科学 材料科学 材料科学
背景情况:
- 希夫基是多功能联结体,在传感和催化中具有应用.
- 开发对金属离子有选择性和敏感的传感器对于环境和生物监测至关重要.
- 与其母联体相比,金属复合体通常表现出增强的生物活动.
研究的目的:
- 为了合成和描述一种新型的Schiff基底传感器 (SBS).
- 评估SBS对各种金属离子的传感能力.
- 研究SBS及其金属复合物的抗菌活性.
主要方法:
- 使用光和1H NMR光谱学合成和描述希夫基底传感器 (SBS).
- 通过光谱学评估金属离子感应选择性和灵敏度.
- 确定目标金属离子的检测极限 (LOD).
- 对各种细菌菌株的抗菌活性的评估.
主要成果:
- SBS对Ag+和Fe3+离子具有很高的选择性和敏感性,在结合时具有显著的光变化.
- 对Ag+的检测极限 (LOD) 是0.0028 ppm,对于Fe3+是0.0016 ppm.
- 与自由联体相比,希夫基础金属复合物 (SBS-Ag+和SBS-Fe3+) 显示出增强的抗菌活性.
结论:
- 新型的Schiff基传感器 (SBS) 对于选择性检测Ag+和Fe3+离子是有效的.
- 与Ag+和Fe3+的协调增强了希夫基的抗菌功效.
- 希夫基及其金属复合物对化学传感和抗菌疗法的应用具有前景.
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