城市和农村白三叶草种群的选择性扫描的签名
James S Santangelo1, Marc T J Johnson2,3,4, Rob W Ness2,3,4
1Department of Integrative Biology, University of California Berkeley, Berkeley, California, USA, 94720.
概括
城市和农村环境都推动了白三叶草种群的进化变化. 基因组分析揭示了在这些对比的息地中对非生物压力和发展的独特遗传适应.
科学领域:
- 进化生物学是进化的生物学.
- 基因组学就是基因组学.
- 生态生态学 生态生态学
背景情况:
- 城市化是进化变化的重要驱动力,但农村息地也施加强大的选择性压力.
- 了解适应不同城市和农村环境的遗传基础至关重要,但仍然有限.
- 城市和农村人口之间的表型差异已得到充分记录,但基本的遗传机制尚不清楚.
研究的目的:
- 确定城市和农村白三叶草种群中积极选择的基因组特征.
- 调查城市和农村息地之间的选择强度和目标是否不同.
- 探索基因架构,使其能够适应当代人为环境.
主要方法:
- 在加拿大多伦多的城市,郊区和农村地区,对120棵白三叶草植物的全基因组测序.
- 对基因组数据的分析,以检测积极选择和临床等位基因频率变化的特征.
- 鉴定与适应不同息地相关的基因区域和基因.
主要成果:
- 在城市和农村白叶三叶草种群中都有积极选择的证据,特别是在与非生物压力耐受性和生长/发展相关的基因中.
- 在选定的基因组区域内检测异基因频率的临床变化.
- 识别不完整的选择性扫描重叠已知的大效应结构变异.
结论:
- 城市和农村的息地都对白三叶草种群施加了重大和持续的选择.
- 这项研究提供了对适应各种人为景观的遗传基础的见解.
- 未来的研究应该专注于解开生态重要表型的遗传结构,以适应当代息地.
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