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Updated: Sep 16, 2025

Quantitative 3D Imaging of Trypanosoma cruzi-Infected Cells, Dormant Amastigotes, and T Cells in Intact Clarified Organs
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Quantitative 3D Imaging of Trypanosoma cruzi-Infected Cells, Dormant Amastigotes, and T Cells in Intact Clarified Organs

Published on: June 23, 2022

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由Trypanosoma cruzi细胞外囊泡和免疫复合体诱导的心脏变化

Alberto Cornet-Gomez1, Francisco O'Valle2,3,4, José M Garrido2,5,6

  • 1Department of Parasitology, Biochemical and Molecular Parasitology Group CTS-183, and Institute of Biotechnology, University of Granada, Granada, Spain.

PLoS neglected tropical diseases
|July 7, 2025
PubMed
概括

来自Trypanosoma cruzi的细胞外囊泡 (EV),与IgG形成免疫复合体,在小鼠中诱导心脏损伤,模仿查加斯病心肌病变. 这些EV被确定为潜在的毒性因素,有助于查加斯病的进展.

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