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通过使用聚烯酸作为灵活的框架材料来有效利用杀菌剂的总体策略

Weiyao Yan¹, Yuqi Huang¹, Gang Tang¹

¹State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing 100193, China.

Journal of advanced research

|July 7, 2025

概括

硫化铜纳米颗粒 (CuS NPs) 为微生物杀菌剂提供了pH响应的纳米输送系统,提高了它们的有效性和植物安全性. 该战略改善了杀菌剂的利用,并支持可持续的植物疾病管理.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
农业科学农业科学

背景情况:

硫化铜纳米颗粒 (CuS NPs) 是优秀的抗菌剂,具有低毒性和可控制的结构,非常适合控制释放纳米系统.
CuS NPs可以提高杀菌剂的利用效率和环境安全.

研究的目的:

了解响应pH的CuS NP纳米递送系统中的药物加载和释放规则.
制定一项有效使用微生物杀菌剂和可持续管理植物疾病的总体战略.

主要方法:

使用聚烯酸 (PAS) 作为框架制造了三种含有微生物杀菌剂的CuS NP (Microbicide@PAS-CuS NP).
加载的柏柏林硫酸盐 (BBR),青素 (BNP) 和卡苏加米辛 (KSM) 作为杀菌剂.
系统评估物理化学特性,生物活性,持续时间,基因毒性和植物安全性.

主要成果:

封装效率和装载能力随着微生物杀菌剂LogP值的降低而增加.
Microbicide@PAS-CuS NPs显示出统一的尺寸,良好的稳定性和高负载率 (21.3637.50%).
在酸性环境下,NP对受控释放,增强光稳定性 (KSM: 15.11x,BNP: 2.84x),改善抗微生物活性,延长寿命和提高植物安全性作出反应.

结论:

制定了一项通用战略,以提高杀菌剂利用效率和环境安全.
Microbicide@PAS-CuS NPs显示了作为可持续农业的新兴刺激响应控制释放纳米输送系统的潜力.

关键词:

在CuS NP中,使用的是CuS NP.纳米囊纳米囊纳米囊一个合成合成.聚烯酸的酸聚烯酸.响应pH值的受控释放.

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