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Updated: May 6, 2026

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半溶解,形成水凝的聚合物微针的工程和体外评估,用于持续释放药物输送

Tarek M Abdelghany1, Nga Vo2, Djurdja Vukajlovic3

  • 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt; Institute of Education in Healthcare and Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresthill, Aberdeen AB25 2ZD, United Kingdom; School of Biomedical, Nutritional and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne NE24HH, United Kingdom.

International journal of pharmaceutics
|July 7, 2025
PubMed
概括

这项研究引入了新的半溶解,形成水凝的微针阵列补丁 (MAPs),用于持续的药物输送. 这些先进的MAP提供高药物负载和长期释放的甲酸 (DSP) 超过两个月.

关键词:
交叉连接 (crosslinking) 是一种交叉连接.微针阵列补丁微针阵列补丁非Fickian的药物释放方式聚合物矩阵是一种聚合物矩阵.皮肤 皮肤 皮肤 皮肤通过皮肤通过皮肤.

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