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Updated: Jun 25, 2026

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons
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相互c-Abl-GPx1调节通过ERK1/2-DRP1介导的线粒体动力学来控制CA1神经元对氧化应激的活力

Ji-Eun Kim1, Su Hyeon Wang1, Tae-Cheon Kang1

  • 1Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon, 24252, South Korea.

Neuropharmacology
|July 7, 2025
PubMed
概括

在氧化应激过程中,c-Abl和谷氨过氧化酶-1 (GPx1) 之间的调节受损会导致CA1神经元死亡. 这通过破坏控制线粒体分裂的ERK1/2-DRP1通路而发生.

关键词:
BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO BSO克里布 (Creb) 是一个非常重要的数字.是一种病.伊马替尼布 (Imatinib) 的使用情况在NAC中,NAC是NAC的代表.发作 发作 发作U0126 这是一个很好的例子.WY14643 是一个很好的选择.

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