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盐在抑郁和焦虑中起什么作用? 一个前性队列研究
Luyi Zhu1, Yixuan Pan2, Jiali Xie3
1Department of Rehabilitation Medicine, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China; Department of Neurology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China.
Journal of affective disorders
|July 7, 2025
概括
经常在食物中添加盐会增加焦虑和抑郁的风险. 吃足够的水果和蔬菜可以降低这些风险,强调饮食对心理健康的影响.
科学领域:
- 营养精神病学 营养精神病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 过度摄入盐与许多健康问题有关.
- 对盐的摄入量和心理健康,特别是焦虑和抑郁症的研究是有限的.
研究的目的:
- 调查食品添加盐的频率与发展焦虑和抑郁症的风险之间的联系.
- 探索饮食中的潜在缓解因素.
主要方法:
- 一项前性队列研究涉及276,138名英国生物库参与者,最初没有焦虑和抑郁症.
- 考克斯的比例危险模型被用来分析盐添加频率与发生焦虑/抑郁之间的关系.
- 随访时间的中位数为14.6年.
主要成果:
- 将盐添加到食物的频率更高与抑郁症 (p-趋势<0.001) 和焦虑症 (p-趋势<0.001) 的风险增加有显著关联.
- 与从未/很少添加盐的人相比,总是添加盐的人患抑郁症的风险增加了45%,焦虑症的风险增加了24%.
- 充分摄入水果和蔬菜表明对这些风险有显著的改变作用 (p-相互作用=0.049对抑郁症,0.031对焦虑症).
结论:
- 增加对食物添加盐的频率是发展焦虑和抑郁症的危险因素.
- 摄入足够的水果和蔬菜可以抵消与高盐消费相关的负面心理健康影响.
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