术前高血糖和非心脏手术后心脏不良事件之间的关联:一个多中心队列研究
Byungjin Choi1,2, Ah Ran Oh3, Jungchan Park1,3
1Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.
Korean journal of anesthesiology
|July 7, 2025
概括
术前急性高血糖症增加了非心脏手术后一年内心脏不良事件的风险. 在年轻患者和没有高血压的患者中,这种风险更高.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 外科手术的结果
背景情况:
- 多中心分析调查了手术前急性高血糖症及其与术后心脏不良事件的联系.
- 急性高血糖症是由手术前24小时内特定的血糖水平来定义的.
研究的目的:
- 为了确定手术前急性高血糖和非心脏手术后心脏不良事件之间的关联.
- 分析风险因素和受这种关联影响的患者子组.
主要方法:
- 利用了来自10家医院的数据,转换为观察医疗结果伙伴关系共同数据模型.
- 包括318,119名接受非心脏手术的成年患者,以及手术前的葡萄糖测量.
- 雇员 1:2 倾向性得分匹配 (PSM) 用于分析.
主要成果:
- 急性高血糖症与26%的心脏不良事件风险增加有关 (HR,1.26;P < 0.001).
- 年轻的患者 (≤65岁) 与老年患者 (HR,1.13) 相比,风险明显更高 (HR,1.61).
- 没有高血压的患者比患有高血压的患者有更大的风险 (HR, 1.37) (HR, 1.09).
结论:
- 手术前急性高血糖症与手术后一年的不良心脏事件有关.
- 需要进一步的研究来探索血糖控制是否可以预防外科手术期间的心脏并发症.
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