[T]

K Huang1, L L Zhang1, C Qiu1

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China Tianjin Institutes of Health Science, Tianjin 301600, China.

概括

T细胞大颗粒性淋巴细胞白血病 (T-LGLL) 涉及免疫细胞失衡,包括过度活跃的CD8+ T细胞和较少的调节性T (Treg) 细胞. 治疗恢复Treg数量并降低T细胞效应者的活性,改善免疫平衡.