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Updated: Sep 16, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Published on: May 13, 2019

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RECQL5诱导的RNA聚合酶II转录制动和随后的重新激活的结构基础

Luojia Zhang1, Yuliya Gordiyenko1, Tomos Morgan1

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature structural & molecular biology
|July 7, 2025
PubMed
概括

RECQL5减缓了RNA聚合酶II (Pol II) 的转录延长. 转录合DNA修复 (TCR) 复合物克服了这种制动,平衡了转录效率和基因组稳定性.

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