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美国老年人饮食中的铜摄入量与认知功能之间的关联:NHANES 2011-2014年
Weiai Jia1, Kangsheng Zhu1, Jingpu Shi1
1Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, 12th Health Road, Shijiazhuang, 050011, Hebei, People's Republic of China.
Scientific reports
|July 7, 2025
概括
饮食中较高的铜摄入量与美国老年人更好的认知功能有关. 这种关联在多个认知测试中观察到,这表明铜.
科学领域:
- 营养神经科学 营养神经科学
- 老年学是一门学科.
- 公共卫生 营养 公共卫生 营养
背景情况:
- 认知能力下降是老年人群的一个重大问题.
- 饮食因素在维持认知健康方面起着至关重要的作用.
- 铜是各种生物过程中必不可少的微量元素,包括神经功能.
研究的目的:
- 研究美国老年人饮食中的铜摄入量与认知功能之间的关联.
- 探索铜摄入量与认知表现之间的潜在非线性关系.
- 为了确定最佳的饮食铜摄入水平,以促进认知健康.
主要方法:
- 使用来自国家健康和营养检查调查 (NHANES) (2011-2014) 的数据进行的横截面观察研究.
- 对2420名参与者的分析,通过24小时回忆来评估饮食中的铜摄入量.
- 用数字符号替换测试 (DSST),动物流利测试 (AFT),CERAD子测试和全球认知Z分数来评估认知功能.
主要成果:
- 饮食中较高的铜摄入量与认知测试中较高的分数显著相关.
- 在完全调整的模型中,最高四分位数的铜摄入量与最低四分位数相比显示出更好的认知得分.
- 非线性分析揭示了铜摄入量与认知功能之间的反向L形关系,在DSST,AFT和Z分数中确定了拐点.
结论:
- 饮食中的铜摄入量与美国老年人的认知功能有关.
- 为了支持认知健康,可能存在最佳的铜摄入范围.
- 需要进一步的纵向研究来证实这些发现并阐明因果关系.
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